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Medical Laboratory Journal، جلد ۱۶، شماره ۶، صفحات ۲۰-۲۵
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عنوان انگلیسی Association between C-Reactive Protein Test Result and Clinical Characteristics in Patients with COVID-19
چکیده انگلیسی مقاله Background and objectives: In coronavirus disease 2019 (COVID-19), elevated serum levels of C-reactive protein (CRP), a marker of systemic inflammation, are commonly observed. We aimed to investigate the associations between CRP test results and clinical characteristics in patients with COVID-19. Method: In this cross-sectional study, data from 399 patients with COVID-19 were collected through a census method. The patients were divided into a CRP-positive group (n=335) and a CRP-negative group (n=64). Demographical data, laboratory findings, clinical characteristics, and history of some underlying diseases were compared between the two groups. All analyses were carried out in SPSS (version 21). Results: The frequency of hypertension was 40.1% among the study population, 42.4 % among CRP-positive patients, and 28.1% among CRP-negative patients. Diabetes and heart disease were the most common comorbidities among the patients. Dyspnea (60.4%), fever (52.7%), fatigue (45.4%), and dry cough (40.1%) were the most commonly observed symptoms. The mean duration of hospitalization was 8.14±6.18 days, and the mean duration of intensive care unit stay was 9.09±9.41 days. Moreover, CRP positivity was significantly associated with hypertension, immunosuppressive therapy, and higher duration of hospitalization (p< 0.05). Conclusion: Pre-existing hypertension, diabetes, and heart disease with the coincidence of some clinical symptoms are associated with higher levels of CRP in COVID-19 patients, which results in longer hospitalization.
کلیدواژه‌های انگلیسی مقاله COVID-19 Testing,SARS-CoV-2,C-reactive protein
نویسندگان مقاله | Maryam Yaseri
Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran


| Seyyedeh Sahereh Mortazavi Khatibani
Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran


| Arvin Naeimi
Student Research Committee, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran


| Haniyeh Sadat Fayazi
Department of Internal Medicine, School of Medicine, Razi Hospital, Guilan University of Medical Sciences, Rasht, Iran
نشانی اینترنتی http://mlj.goums.ac.ir/browse.php?a_code=A-10-1321-1&slc_lang=en&sid=1
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زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده علوم آزمایشگاهی
نوع مقاله منتشر شده Research Article
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