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Journal of Research in Medical Sciences، جلد ۲۷، شماره ۲۰، صفحات ۲۰۲۲-۲۷
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عنوان انگلیسی Prognostic factors in traumatic brain injuries in emergency department
چکیده انگلیسی مقاله Background : Traumatic brain injury (TBI) is a leading cause of morbidity and mortality in young adults. The Extended Glasgow Outcome Score GOSE) has been introduced to assess the global outcome after brain injuries. Therefore, we aimed to evaluate the prognostic factors ssociated with GOSE. Materials and Methods: This was a multicenter ross?sectional study conducted on 144 patients with TBI admitted at trauma emergency centers. The patients’ information, including emographic characteristics, duration of hospital stay, mechanical ventilation and on?admission laboratory measurements, and n?admission vital signs, were evaluated. The patients’ TBI?related symptoms and brain computed tomography (CT) scan findings were recorded. Results: GOSE assessments showed an increasing trend by the comparison of n?discharge (7.47 ± 1.30), within a month (7.51 ± 1.30) and within 3 months (7.58 ± 1.21) evaluations (P < 0.001). On?discharge GOSE was ositively correlated with Glasgow Coma Scale (GCS)(r = 0.729, P < 0.001), motor GCS (r = 0.812, P < 0.001), Hb (r = 0.165, P = 0.048), and pH (r = 0.165, P = 0.048) and inversely with age (r = ?0.261, P = 0.002), hospitalization period (r = ?0.678, P < 0.001), pulse rate (r = ?0.256, P = 0.002), white blood cell (WBC) (r = ?0.222, P = 0.008), and triglyceride (r = ?0.218, P = 0.009). In multiple linear regression analysis, the associations were significant only for GCS (B = 0.102, 95% confidence interval [CI]: 0–0.202; P = 0.05), hospitalization stay duration (B = ?0.004, 95% CI: ?0.005–?0.003, P = 0.001), and WBC (B = .00001, 95% CI: .00000014–0.000025; P = 0.024). Among imaging signs and trauma?related symptoms in univariate analysis, intracranial hemorrhage (ICH), interventricular hemorrhage (IVH) (P = 0.006), subarachnoid hemorrhage (SAH) (P = 0.06; marginally at P < 0.1), subdural hemorrhage (SDH) (P = 0.032), and epidural hemorrhage (EDH) (P = 0.037) was significantly associated with GOSE at discharge in multivariable analysis. Conclusion: According to the current study findings, GCS, hospitalization stay duration, WBC and among imaging signs and trauma?related symptoms ICH, IVH, SAH, SDH, and EDH are independent significant predictors of GOSE at discharge in TBI patients.
کلیدواژه‌های انگلیسی مقاله Computed tomography, Glasgow Coma Scale, Glasgow Outcome Scale, traumatic brain injuries, X?ray
نویسندگان مقاله | Mohammad Javad Behzadnia


| Mousareza Anbarlouei


| Seyed Morteza Hosseini


| Amir Bahador Boroumand


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/11392
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Article
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