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Infection Epidemiology and Microbiology، جلد ۷، شماره ۱، صفحات ۷۷-۹۹
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Prevalence of Imipenem-Resistant Acinetobacter baumannii isolates in Iran: A Meta-Analysis |
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| چکیده انگلیسی مقاله |
Background: Acinetobacter baumannii is a gram-negative pathogen that is highly resistant to antibiotics. This bacterium can cause severe systemic infections, especially in hospitalized patients. Recently, antimicrobial-resistant Acinetobacter baumannii has become a life-threatening pathogen in Iran and around the world. Materials & Methods: In this study, several Iranian and English databases were systematically searched to find all original and review articles investigating the prevalence of imipenem resistance in their sample size, while mentioning the source of clinical isolates, as well as the prevalence of antimicrobial resistance genes. Findings: Among genes, blaOXA-23 with a prevalence of 31% to 100% was responsible for global outbreaks of imipenem-resistant Acinetobacter baumannii and was presented in most of the hospital isolates. Our meta-analysis also revealed that 74.2% of Acinetobacter baumannii were resistant to imipenem in 122 clinical studies. Conclusion: Our study highlighted a rapid increase in the rate of imipenem resistance in clinical isolates of Acinetobacter baumannii in Iran. The need for periodic antibiotic care system programs to monitor the administration and use of antibiotics |
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| کلیدواژه‌های انگلیسی مقاله |
Imipenem, Resistance, Acinetobacter baumannii, Iran. |
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| نویسندگان مقاله |
| Mozhgan Derakhshan Sefidi
Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
| Leila Heidary
Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran
| Saeed Shams
Cellular and Molecular Research Center, Qom University of Medical Sciences, Qom, Iran
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| نشانی اینترنتی |
http://iem.modares.ac.ir/browse.php?a_code=A-10-57892-1&slc_lang=en&sid=4 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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