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Iranian Journal of Public Health، جلد ۵۱، شماره ۸، صفحات ۱۸۱۷-۱۸۲۶
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عنوان انگلیسی Combination of Serum Test and Questionnaire in Early Gastric Cancer Screening
چکیده انگلیسی مقاله Background: We aimed to analyze the predictive role of serum test and questionnaire in Early Gastric Cancer in The First Affiliated Hospital of Xingtai Medical College, Hebei Province from 2019 to 2020. Methods: In this prospective study, 280 medical examiners underwent questionnaire, serum test and gastroscopy. They were divided into Gastric cancer (GC) and Non-Gastric cancer (NGC) group. NGC group was divided into Low-grade intraepithelial neoplasia (LGIN), Chronic atrophic gastritis (CAG) and Non-chronic atrophic gastritis (NCAG) group. Results: Age, drinking, sex and Gastrin-17(G-17) was respectively independent risk factors for GC. Age, drinking and G-17 was independent risk factors for GC in men. G-17 of GC group was higher than that of LGIN and NCAG group (P< 0.05). Pepsinogen I/II ratio (PGR) of GC was lower than that of NCAG group (P< 0.05). There was no significant difference between Pepsinogen I (PGⅠ) and Pepsinogen II (PGII) in the four groups. Helicobacter pylori-immunoglobulin G antibodies (H. pylori-IgG) of LGIN group was significantly higher than that of CAG and NCAG group in gastritis group (P< 0.008). G-17≥42.95 pmol/L, age≥69years, male and drinking can predict GC. Conclusion: Older, drinking, men and high G-17 could respectively predict GC. Especially in men, older, drinking and high G-17 could affect the occurrence of GC. G-17, age, drinking and sex used respectively to screen high-risk populations for GC were more efficient than combined screening. GC had a higher serum G-17 and a lower PG than other gastric diseases.
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نویسندگان مقاله | Qiang Li
The First Affiliated Hospital of Xingtai Medical College, Xingtai, Hebei Province, China


| Yibing Liu
Department of Medical Oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei Province, China


| Zhe Meng
The First Affiliated Hospital of Xingtai Medical College, Xingtai, Hebei Province, China


| Qingfeng Ge
The First Affiliated Hospital of Xingtai Medical College, Xingtai, Hebei Province, China


| Liyan Zhao
The First Affiliated Hospital of Xingtai Medical College, Xingtai, Hebei Province, China


| Huiying Chu
The First Affiliated Hospital of Xingtai Medical College, Xingtai, Hebei Province, China


| Xiaomin Li
The First Affiliated Hospital of Xingtai Medical College, Xingtai, Hebei Province, China


| Jingli Chen
Hebei Medical University, Shijiazhuang, Hebei Province, China


| Qingju Meng
The First Affiliated Hospital of Xingtai Medical College, Xingtai, Hebei Province, China
نشانی اینترنتی https://ijph.tums.ac.ir/index.php/ijph/article/view/27643
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