مجله تغذیه و امنیت غذایی، جلد ۷، شماره ۲، صفحات ۱۵۰-۱۵۹

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عنوان انگلیسی The Relationship between Antioxidants Consumption and Insulin Resistance/Insulin Sensitivity in Type 2 Diabetes without and with Coronary Stenosis: A Case-Control Study
چکیده انگلیسی مقاله Background: Type 2 diabetes (T2D) is known as a common chronic metabolic disease worldwide. Coronary artery diseases are one of the hazardous disorders in diabetic patients. The current study aimed to investigate the relationship between dietary antioxidants intake with insulin resistance and insulin sensitivity among T2D without and with coronary stenosis (CS). Methods: This case-control study was conducted on 247 participants (65 diabetic patients suffered from CS and 172 diabetic patients without CS). Dietary antioxidants intake (vitamin E, Vitamin C, selenium, beta-carotene, and zinc) were assessed with a valid and reliable 168-item semi-quantitative food frequency questionnaire (FFQ). Blood pressure, weight, and height were measured. Blood sample was collected for glycaemic control assessment. Results: Diabetic patients with CS had significantly higher HbA1c levels (P = 0.004). There was a negative significant association between vitamin E (r = -0.91; P < 0.001) and Beta-carotene (r =-0.88; P < 0.001) with HbA1c among all participants. There was also a positive significant association between vitamin E, vitamin C, and selenium with insulin sensitivity among all the participants; (r = 0.59; P = 0.004) for vitamin E, (r = 0.91; P < 0.001) for vitamin C, and (r = 0.27; P = 0.04) for Beta-carotene. Conclusion: Antioxidants intake especially vitamin C and beta-carotene may have an anti-insulin resistance effect in metabolic disorders
کلیدواژه‌های انگلیسی مقاله Diabetes mellitus, Coronary stenosis, Dietary intake, Antioxidants, Insulin resistance

نویسندگان مقاله | Hadis Gerami
Nutrition and Food Security Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran


| Atena Jamalzehi
Department of Nutrition, School of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran


| Maryam Javadi
Children Growth Research Center, Qazvin University of Medical Sciences, Qazvin, Iran


| Seyed Kianoosh Hosseini
Department of Cardiology, Tehran University of Medical Sciences, Tehran, Iran


| Azadeh Lesani
Department of Nutrition and Biochemistry, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.



نشانی اینترنتی http://jnfs.ssu.ac.ir/browse.php?a_code=A-10-149-2&slc_lang=en&sid=1
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