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Journal of Ultrafine Grained and Nanostructured Materials، جلد ۵۳، شماره ۲، صفحات ۱۸۳-۱۸۹
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Preparation and physical characterization of Adonis vernalis aqueous leaf extract-mediated green synthesized silver nanoparticles and its toxicity effect on breast cancer cells |
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| چکیده انگلیسی مقاله |
The specific characteristics of silver nanoparticles (AgNPs), especially anticancer and antimicrobial properties, have led to their widespread usage in biology. The study looked at the anti-cancer activity of AgNPs, which were produced by a one-step green synthesis based on the use of Adonis vernalis leaf extract. Characterization of reducing agents in plant extracts was performed using (FT-IR) infrared spectroscopy. The presence of adsorption peak at 442 nm in UV-visible absorbance of bio-fabricated AgNPs indicates the effectiveness of proposed method. Transmission electron microscope (TEM) and field emission electron microscope (FESEM) were used to investigate the morphology and confirmed the spherical shape of products. Phase analysis and determination of the synthesized product crystal lattice was performed using X-ray diffraction (XRD) method. The stability of particles was determined using zeta potential analyze. Energy-dispersive X-ray (EDX) analysis confirmed the formation of high purity AgNPs. The MTT assay was used to determine the anti-toxic properties of produced products and the results demonstrated that silver nanoparticles biosynthesized by Adonis vernalis extract can be used to treat breast cancer. |
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| کلیدواژه‌های انگلیسی مقاله |
Green Synthesis, Silver nanoparticles, Adonis vernalis extract, Breast Cancer, MTT assay |
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| نویسندگان مقاله |
Roshana Sattari |
Department of Materials Science and Engineering, Shahid Bahonar University of Kerman, Kerman, Iran.
Gholam Reza Khayati |
Department of Materials Science and Engineering, Shahid Bahonar University of Kerman, Kerman, Iran.
Reyhane Hoshyar |
Cellular and Molecular Research Center, Department of Biochemistry, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran.
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| نشانی اینترنتی |
https://jufgnsm.ut.ac.ir/article_79221_2a7bbf946a88077b97e1176f29108087.pdf |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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