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Iranian Journal of Fisheries Sciences، جلد ۱۹، شماره ۶، صفحات ۳۱۷۰-۳۱۸۲
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Research Article: The effects of copper-based nanoparticles on the immune system of the white shrimp (Penaeus vannamei) |
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| چکیده انگلیسی مقاله |
The application and development of nanotechnology is increasingly expanded in many areas. However, considering this expansion, several concerns regarding their potential toxicity in marine biology have been addressed. Indeed, the overuse of these materials can adversely influence marine ecosystems and living organisms. Herein, the potential impact of copper-based nanoparticles on the expression level of three genes, i.e. prophenoloxidase, serine protein and glutathione peroxidase genes functioning in shrimp immune response, were assessed. For this end, the shrimps were exposed to three semi-acute toxicity treatments, including 0.25, 0.5 and 1 mg/L of CuNPs. The qRT-PCR results indicated negative effect of supplied nanoparticle on the expression level of these genes. Additionally, histopathological alterations in the hepatopancreas and lymphoid organs were observed in the shrimps after exposure in different concentrations of CuNPs. Overall, we showed that toxic concentration of CuNPs can damage shrimp immune system as well as some internal organs. These results open up novel insights into innate immunity of shrimps subjected to copper-based nanoparticles. |
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| کلیدواژه‌های انگلیسی مقاله |
White shrimps, CuNPs, Immune system, Hepatopancreas, Lymphoid organs |
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| نویسندگان مقاله |
| H. Sadralsadati
, Science and Research Branch, Islamic Azad University, Tehran, Iran
| A. Mashinchian Moradi
, Science and Research Branch, Islamic Azad University, Tehran, Iran
| M. Afsharnasab
Department of Veterinary Science, Science and Research Branch, Islamic Azad University, Tehran, Iran
| P. Ghavam Mostafavi
, Science and Research Branch, Islamic Azad University, Tehran, Iran
| E. Ramezanifard
, Science and Research Branch, Islamic Azad University, Tehran, Iran
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| نشانی اینترنتی |
http://jifro.ir/browse.php?a_code=A-10-3204-1&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Genetics |
| نوع مقاله منتشر شده |
پژوهشی |
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