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JCR 2016
جستجوی مقالات
جمعه 21 شهریور 1404
Caspian Journal of Enviromental Sciences
، جلد ۱۸، شماره ۵، صفحات ۴۹۵-۵۰۲
عنوان فارسی
چکیده فارسی مقاله
کلیدواژههای فارسی مقاله
عنوان انگلیسی
The role of mast cells, C-fibers, and cholinergic transmission in the reduction of tracheal muscle and mronchi of sensitized animal
چکیده انگلیسی مقاله
The article considers the role of stabilization of mast cell membranes, blockade of neuromuscular transmission and inactivation of C-fibers in the contractile activity of smooth muscles of the trachea and bronchi of sensitized rats. The studies were conducted on isolated preparations using electrical stimulation of postganglionic nerves (frequency - 30 stim/s, duration - 0.5 ms, amplitude - 20 V, duration of stimulation - 10 s). The study used cromolyn sodium, atropine, and capsaicin. As a result of the experiments, it was found that the leading role in the contraction of the muscles of the trachea and bronchi of a sensitized rat belongs to mast cells. However, the maximum effect of normalization of smooth muscle contraction can be achieved only in the case of a complex effect - blockade of neuromuscular transmission, stabilization of mast cell membranes, and inactivation of C-fibers.
کلیدواژههای انگلیسی مقاله
Romolyn sodium, Atropine, Capsaicin, Acetylcholine receptor blockade, Electrical stimulation, Postganglionic nerves
نویسندگان مقاله
V.M. Kirilina |
Department of Life Safety and Health-saving Technologies, Federal State Budgetary Educational Institution of Higher Education «Petrozavodsk State University, Petrozavodsk, The Republic of Karelia, the city of Petrozavodsk, Russia
L.E. Blazhevich |
Department of Life Safety and Health-saving Technologies, Federal State Budgetary Educational Institution of Higher Education «Petrozavodsk State University, Petrozavodsk, The Republic of Karelia, the city of Petrozavodsk, Russia
O.E. Smirnova |
Department of Life Safety and Health-saving Technologies, Federal State Budgetary Educational Institution of Higher Education «Petrozavodsk State University, Petrozavodsk, The Republic of Karelia, the city of Petrozavodsk, Russia
نشانی اینترنتی
https://cjes.guilan.ac.ir/article_4477_ae492cb8b8f54e5df47435bb268f71a6.pdf
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