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Bulletin of Emergency and Trauma، جلد ۹، شماره ۴، صفحات ۱۸۳-۱۸۷
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
S100 Calcium-Binding Protein B and Glial Fibrillary Acidic Protein in Patients with Mild Traumatic Brain Injury |
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| چکیده انگلیسی مقاله |
Objective: To examine the GFAP and S100B ability in prevention unnecessary brain CT scan in mTBI and compare them with the single extremity fracture in orthopedic patients. Methods: In this prospective cohort study, two orthopedics patients’ groups and mTBI patients were studied to assess the biomarkers’ ability in prevention unnecessary brain CT scan at the emergency setting. There were 40 orthopedics’ patients with single extremity fracture and 41 mTBI patients. Brain CT scans were done for all mTBI patients. Results: Brain CT scans showed no intracranial traumatic lesions. The median levels for S100B in the mTBI group was 14.8 (4.4-335.9) ng/L, and in orthopedic patients’ group was 13.3 (5-353.10) ng/L. Statistically significant differences were observed between both groups in S100B levels (p=0.006). The median Glial Fibrillary Acidic Protein (GFAP) levels in the mTBI patients’ group were 600 (400-16300) and in the orthopedic patients’ groups was 60 ng/L (300-14900). Statistically significant differences were observed between groups in GFAP (p=0.041). Conclusion: Our results showed that S100B and GFAP serum levels were significantly higher in patients with mTBI than in patients with a single limb fracture. |
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| کلیدواژه‌های انگلیسی مقاله |
Glial fibrillary acidic protein, S100B, Computed tomography scan, Traumatic brain injury |
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| نویسندگان مقاله |
Ali Meshkini |
Road Injuries Prevention Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Amir Ghorbani |
Biotechnology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Zahra Hasanpour Segherlou |
Road Injuries Prevention Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
Masoud Nouri-Vaskeh |
Medical Philosophy and History Research Center, Tabriz University of Medical Sciences, Tabriz, Iran
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| نشانی اینترنتی |
https://beat.sums.ac.ir/article_47631_ff54b87a5957765a325dab67689d4bb4.pdf |
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| زبان مقاله منتشر شده |
en |
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