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Journal of Pediatrics Review، جلد ۹، شماره ۳، صفحات ۲۱۹-۲۲۸
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عنوان انگلیسی Stem Cell Therapy in Children With Sensorineural Hearing Loss: A Narrative Review
چکیده انگلیسی مقاله Context: One of the research areas is using stem cell transplantation for treating children's sensorineural hearing loss. Preclinical studies and testing of the stem cell types have been performed in this field, and relative improvement has been achieved.  Objectives: This narrative review has been prepared to study the advancements in hearing regeneration with stem cell transplantation. Data Sources: The English articles with full-text were searched in PubMed, Scopus, and Google scholar from 2000 to 2020 using keywords of sensory neural hearing loss and stem cell. Results: In 2018, the first human study was performed with stem cells from the human umbilical cord, which has promising results regarding the safety of the method and its positive effects on hearing. Conclusions: Autologous stem cell transplantation had induced relative improvement without serious adverse events in children with acquired sensorineural hearing loss. To obtain more evidence, further studies are required with larger sample sizes and in different patients groups.
کلیدواژه‌های انگلیسی مقاله Children, Sensorineural hearing loss, Stem cell
نویسندگان مقاله | Mahbobeh Oroei
Department of audiology, rehabilitation Research Center, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran , Iran.


| Mohsen Ahadi
Department of audiology, rehabilitation Research Center, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran , Iran.
نشانی اینترنتی http://jpr.mazums.ac.ir/browse.php?a_code=A-10-933-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Pediatrics
نوع مقاله منتشر شده Narrative Review
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