|
|
Iranian Journal of Neonatology، جلد ۱۲، شماره ۲، صفحات ۲۷-۳۲
|
|
|
| عنوان فارسی |
|
|
| چکیده فارسی مقاله |
|
|
| کلیدواژه‌های فارسی مقاله |
|
|
| عنوان انگلیسی |
Ultrasonographic Changes of the Uterus and Ovaries in Female Infants with Congenital Adrenal Hyperplasia: Pseudo-Testicular Sign |
|
| چکیده انگلیسی مقاله |
Background: Congenital Adrenal Hyperplasia (CAH) is one of the main causes of ambiguous genitalia. The unusual appearance of internal genitalia in CAH patients is similar to many other conditions which are classified in Disorders of Sex Development (DSD). This study aimed to accurately describe diagnostic ultrasonic features of the uterus and ovaries in CAH patients in order to distinguish it from other causes of ambiguous genitalia. Methods: This cross-sectional study was performed in Akbar Children Hospital, Mashhad University of Medical Sciences, Mashhad, Iran, from 2017 to 2020. Ultrasound findings of the uterus and ovaries of 22 female infants (2-60 days of age) with CAH due to 21-hydroxylase deficiency and 47 healthy infants with a similar age were recorded and eventually analyzed in this study. Results: All the healthy infants in the control group had a normal prominent cervix, except for two neonates (95%). In the case group, only 9 (41%) infants had a normal prominent cervix, and other 13 newborns had nearly equal sizes of fundus and cervix. There was a significant difference between the two groups in the fundus-to-cervix ratio (P=0.009). The 77% patients had no follicles in both ovaries, while 28% healthy infants in the control group had no follicles, and the rest had unilateral or bilateral multi-follicular ovaries. After two months following treatment, bilateral multi-follicular ovaries were observed in all patients. The sign of non-follicular ovaries (pseudo-testicular appearance) was significantly more prevalent in the case group (P=0.004). Furthermore, half of infants showed normal pelvic lymph node that mimic a testicular-like appearance due to its uniform hyper-echoic texture. Conclusion: The testicular-like appearance of normal pelvic lymph nodes and non-follicular ovaries in a female infant with CAH. Attention to these usual findings can prevent misdiagnoses of cryptorchidism and time loss to perform other laboratory tests and karyotyping. |
|
| کلیدواژه‌های انگلیسی مقاله |
Congenital Adrenal Hyperplasia, Disorders of Sex Development, Ovary, Ultrasound |
|
| نویسندگان مقاله |
| Seyed Ali Alamdaran
Radiology Department, Akbar Children Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
| Soroush Dashtabi
Radiology Department, Akbar Children Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
| Armin Sani
Radiology Department, Akbar Children Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
| Vakili Rahim
Endocrine Department, Akbar Children Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
| Somayeh Hashemian
Endocrine Department, Akbar Children Hospital, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran
|
|
| نشانی اینترنتی |
https://ijn.mums.ac.ir/article_16789.html |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
|
| نوع مقاله منتشر شده |
تحقیقی اصیل |
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|