|
|
Medical Laboratory Journal، جلد ۱۵، شماره ۲، صفحات ۲۸-۳۴
|
|
|
| عنوان فارسی |
|
|
| چکیده فارسی مقاله |
|
|
| کلیدواژه‌های فارسی مقاله |
|
|
| عنوان انگلیسی |
Comparison of Combined and Aerobic Training on ABCG1 Lymphocyte Gene Expression in Middle-Aged Men Undergoing Coronary Artery Bypass Grafting |
|
| چکیده انگلیسی مقاله |
Background and objectives: Cardiovascular disease is one of the most important causes of mortality worldwide. The present study aimed to compare two different cardiac rehabilitation protocols on ATP-binding cassette sub-family G member 1 (ABCG1) lymphocyte expression and blood lipid profile in middle-aged men undergoing coronary artery bypass grafting. Methods: Forty five middle-aged men who had previously undergone coronary artery bypass surgery were randomly divided into three groups of control (C; n=15), aerobic training (AT; n=15) and combined training (CT; n=15). Blood samples were taken before the first and after the last exercise sessions. After isolation of mononuclear cells using Ficoll and mRNA purification, gene expression changes were examined by real-time PCR. Data were analyzed using one-way ANOVA and Bonferroni post-hoc tests. Results: Eight weeks of training intervention resulted in a significant increase in ABCG1 expression as well as a significant decrease in plasma levels of LDL, triglyceride and total cholesterol in both training groups. However, there was no significant difference between the AT and CT groups. In addition, high-density lipoprotein was significantly increased in the AT and CT groups. Conclusion: Both AT and CT can increase plasma LDL and increase ABCG1 expression and HDL concentrations, indicating the positive effects of both interventions on the prevention of atherosclerosis. |
|
| کلیدواژه‌های انگلیسی مقاله |
Coronary Artery Bypass,Circuit-Based Exercise,ABCG1,Exercise |
|
| نویسندگان مقاله |
| Rokhsareh Moosavi
Islamic Azad University, Neyshabur Branch, Neyshabur, Iran
| Amir Rashidlamir
Ferdowsi University of Mashhad
| Rambod Khajeie
Islamic Azad University, Neyshabur Branch, Neyshabur, Iran
| Mahmoud Hejazi
Ferdowsi University of Mashhad
|
|
| نشانی اینترنتی |
http://mlj.goums.ac.ir/browse.php?a_code=A-10-597-10&slc_lang=en&sid=1 |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
فیزیولوژی ورزشی |
| نوع مقاله منتشر شده |
تحقیقی |
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|