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Medical Laboratory Journal، جلد ۱۵، شماره ۵، صفحات ۷-۱۲
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Evaluation of in Vitro Antimicrobial Effects of Aqueous Extract of Tribulus terrestris Against Oral Bacteria |
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| چکیده انگلیسی مقاله |
Background and objectives: Medicinal plants have long been considered as one of the most important pillars of traditional medicine. Existing challenges in the treatment of diseases, particularly infectious diseases, are major drivers for herbal medicine studies. Tribulus terrestris has been widely used in traditional medicine to treat various diseases. This study aimed to investigate in vitro antibacterial effect of the aqueous extract of T. terrestris on several oral bacteria. Methods: In this experimental study, after preparing the aqueous extract of T. terrestris, minimum inhibitory and bactericidal concentrations (MIC and MBC) of the extract were determined against standard strains of Streptococcus mutans, Staphylococcus aureus, Klebsiella pneumoniae and Streptococcus pyogenes using the broth microdilution method. The experiments were repeated three times and the results were analyzed with SPSS 22 using the one-way analysis of variance (ANOVA) and LSD statistical tests with the significance level set at 0.05. Results: The aqueous extract of T. terrestris had the highest inhibitory effect on S. pyogenes and S. mutans, and the difference between the MIC and MBC values was significant (P < 0.05). However, no such effect was observed against S. aureus and K. pneumonia at concentrations below 50 mg/ml when compared to ampicillin and chlorhexidine. Conclusion: The aqueous extract of T. terrestris has significant antibacterial effects against S. pyogenes and S. mutans. Therefore, it can be incorporated into topical formulations such as toothpaste and mouthwash products after further in vivo and toxicity experiments. |
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| کلیدواژه‌های انگلیسی مقاله |
Tribulus,Anti-Bacterial Agents,bacteria |
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| نویسندگان مقاله |
| Zahra Kiani
Pharmacology department, Faculty of Pharmacy, Birjand University of Medical Sciences, Birjand, Iran
| Pouria Mohammad Parast Tabas
Student Research Committee, BSc Student in Medical Laboratory Science, Birjand University of Medical Sciences, Birjand, Iran
| khashayar khalilpour
Faculty of Dentistry, Birjand University of Medical Science, Birjand, Iran
| Mahjoube Goldani Moghadam
Orthodontic Department, Faculty of Dentistry, Birjand University of Medical Sciences, Birjand, Iran
| Majid Zare_Bidaki
Infectious Diseases Research Center, Birjand University of Medical Sciences, Birjand, Iran
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| نشانی اینترنتی |
http://mlj.goums.ac.ir/browse.php?a_code=A-10-56-2&slc_lang=en&sid=1 |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
میکروب شناسی |
| نوع مقاله منتشر شده |
Research Article |
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