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Medical Laboratory Journal، جلد ۱۶، شماره ۱، صفحات ۹-۱۲
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Clinical Features of COVID-19 Patients with Preexisting Hypothyroidism: A Retrospective Study |
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| چکیده انگلیسی مقاله |
Background and objectives: Coronavirus disease 2019 (COVID-19) has been reported to be more severe and highly fatal in patients with co-morbidities. Thyroid dysfunction leads to multisystem derangements, as thyroid hormones have major role in the development and functioning of all the human cells. The present study evaluated the variation in the clinical and biochemical parameters of COVID-19 patients with preexisting hypothyroidism. Methods: This retrospective cohort study was carried out on eight COVID-19 patients with hypothyroidism who were admitted to a tertiary care hospital in Mangalore, India. Various clinical and biochemical parameters of the patients were recorded. Results: Out of eight patients, three were men and five were women. With respect to other co-morbidities, six patients had associated type-2 diabetes mellitus and the remaining two patients had no other co-morbidities apart from hypothyroidism. Regarding the severity of COVID-19, one patient had mild symptoms, two had moderate symptoms, and the remaining five patients had severe COVID-19 symptoms. Most biochemical and hematological parameters in all patients were deranged from normal values. Moreover, only 25% of the patients recovered from the disease. Conclusion: Most COVID-19 patients with hypothyroidism had low oxygen saturation and high level of inflammatory markers. In addition, the risk of mortality in COVID-19 patients with hypothyroidism and type 2 diabetes mellitus was higher compared to patients with hypothyroidism alone. It is recommended to closely monitor COVID-19 patients with hypothyroidism and limit the use of steroids during the course of treatment. |
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| کلیدواژه‌های انگلیسی مقاله |
Hypothyroidism,COVID-19,Biomarkers |
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| نویسندگان مقاله |
| PRABHAKAR ADAKE
Yenepoya Medical College, Mangalore
| ABHISHEK ACHARYA
Subbaiah Institute of Medical Sciences
| SUSHEELA HALEMANI
Subbaiah Institute of Medical Sciences
| MAHALAXMI PETIMANI
Yenepoya Medical College, Mangalore
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| نشانی اینترنتی |
http://mlj.goums.ac.ir/browse.php?a_code=A-10-1135-1&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
بیوشیمی |
| نوع مقاله منتشر شده |
Research Article |
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