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Iranian Journal of Public Health، جلد ۵۱، شماره ۲، صفحات ۴۰۹-۴۱۵
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عنوان انگلیسی A Nationwide Study on the Seroprevalence of Measles, Mumps, and Rubella in Iranian Children and Adolescents
چکیده انگلیسی مقاله Background: Assessing the prevalence of infections, which are preventable by vaccination, is crucial to monitor the vaccination program efficacy, and it can demonstrate the gaps in population immunity. The current study attempted to assess the specific Immunoglobulin (IgG) antibody against measles, mumps, and rubella (MMR) in Iranian children and adolescents, years after their vaccination. Methods: This cross-sectional study was conducted in Iran. Serum samples of 2100 students, aged 7-18 years, included in a national health survey, were tested for MMR antibodies by ELISA assay. Multistage random cluster sampling was used to select subjects from 30 provinces in Iran. Results: Overall, 1871, 1718, and 1678 serums were tested for measles, mumps, and rubella antibodies, respectively. The prevalence of positive test was 1231 (65.8%) for measles, 1327 (77.2%) for mumps and 1344 (80.1%) for rubella. Conclusion: Despite high vaccination coverage in Iran, IgG antibody against measles, mumps, and rubella was not detected in a considerable proportion of children and adolescents aged 7-18 years. In case of contacts with residents of other countries, where measles or rubella have not yet been eliminated, it may create problems for Iranian children.
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نویسندگان مقاله | Zary Nokhodian
Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran


| Behrooz Ataei
Nosocomial Infection Research Center, Isfahan University of Medical Sciences, Isfahan, Iran


| Mohammad Mehdi Gouya
Center for Communicable Disease Control, Ministry of Health and Medical Education, Tehran, Iran


| Shervin Ghafari Hosseini
Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran


| Majid Yaran
Infectious Diseases and Tropical Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran


| Marjan Mansourian
Department of Biostatistics and Epidemiology, School of Health, Isfahan University of Medical Sciences, Isfahan, Iran


| Mohammad Esmaeil Motlagh
Department of Pediatrics, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran


| Ramin Heshmat
Chronic Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran


| Seyed Mohsen Zahraei
Nosocomial Infection Research Center, Isfahan University of Medical Sciences, Isfahan, Iran


| Roya Kelishadi
Department of Pediatrics, Child Growth and Development Research Center, Research Institute for Primordial Prevention of Non-communicable Disease, Isfahan University of Medical Sciences, Isfahan, Iran
نشانی اینترنتی https://ijph.tums.ac.ir/index.php/ijph/article/view/18573
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