International Journal of Pediatrics، جلد ۸، شماره ۲، صفحات ۱۰۸۸۹-۱۰۸۹۷
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عنوان انگلیسی Effect of Vitamin D Therapy on Hashimoto's Thyroiditis in Children with Hypovitaminosis D
چکیده انگلیسی مقاله Background Hashimoto's thyroiditis (HT) is a common cause of thyroid diseases in children and the role of vitamin D (VD) is controversial. Therefore, the aim of this study was to investigate the influence of VD therapy on HT in children with hypovitaminosis D. Materials and Methods This randomized clinical trial study was conducted on 30 patients referred to Endocrine Clinic of Amirkola Children's Hospital (ACH) of Babol in Iran. The serum levels of calcium, T4, TSH, Anti thyroid peroxidase antibody (TPOAb), and Anti thyroglobulin antibody (TgAb) were checked, and ultimately the HT was diagnosed based on thyroid sonography and these findings. According to normal range of calcium>8.4 mg/dl and low level of VD, the patients were divided into deficient ( Results The mean of anti-Tg and anti-TPO statistically decreased was 801.63±1172.29 vs. 492.38±1021.48 (p=0.01), and 728.21±1004.28 vs. 441.57±603.26 (p=0.01) before and after intervention, respectively so that this reduction was higher in 2-12 year-old patients. Moreover, the mean of thyroid volume in both right and left lobes statistically reduced was 3.97±3.18 vs. 3.21±2.67 (p=0.002), and 3.32±2.94 vs. 3.21±3.96 (p=0.008) before and after intervention, respectively so this decrease was higher in≥13 year-old children (p
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نویسندگان مقاله | Abdolali Aghili
General Physician, Student Research Committee, Babol University of Medical Sciences, Babol, Iran.


| Morteza Alijanpour Aghamaleki
Assistant Professor of Pediatric Endocrinology, Non-Communicable Pediatric Diseases Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, IR Iran.


| Mohammad Pornasrollah
The Clinical Research Development Unit of Amirkola Children's Hospital, Babol University of Medical Sciences, Babol, IR Iran.


| Haj Ghorban Nooreddini
The Clinical Research Development Unit of Amirkola Children's Hospital, Babol University of Medical Sciences, Babol, IR Iran.


| Soraya Khafri
Department of Biostatistics, School of Medicine, Babol University of Medical Sciences, Babol, Iran.


| Shayan Alijanpour
MSc Students of Critical Care Nursing, Student Research Committee, Isfahan University of Medical Science, Iran.
نشانی اینترنتی http://ijp.mums.ac.ir/article_13961.html
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