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Bulletin of Emergency and Trauma، جلد ۶، شماره Issue ۱، صفحات ۸-۱۵
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| عنوان انگلیسی |
Effects of Aloe Vera and Chitosan Nanoparticle Thin-Film Membranes on Wound Healing in Full Thickness Infected Wounds with Methicillin Resistant Staphylococcus Aureus |
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| چکیده انگلیسی مقاله |
Objective: To assess effect of Aleo vera with chitosan nanoparticle biofilm on wound healing in full thickness infected wounds with antibiotic resistant gram positive bacteria.Method: Thirty rats were randomized into five groups of six rats each. Group I: Animals with uninfected wounds treated with 0.9% saline solution. Group II: Animals with infected wounds treated with saline. Group III: Animals with infected wounds were dressed with chitosan nanoparticle thin-film membranes. Group IV: Animals with infected wounds were treated topically with Aloe vera and Group V: Animals with infected wounds were treated topically with Aloe vera and dressed with chitosan nanoparticle thin-film membranes. Wound size was measured on 6, 9, 12, 15, 18 and 21days after surgery.Results: Microbiology, reduction in wound area and hydroxyproline contents indicated that there was significant difference (p< 0.05) between group V and other groups. Quantitative histological studies and mean rank of the qualitative studies demonstrated that there was significant difference (p< 0.05) between group V and other groups.Conclusion: The Aloe vera with chitosan nanoparticle thin-film membranes had a reproducible wound healing potential and hereby justified its use in practice. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
Reza Ranjbar |
Molecular Biology Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran
Alireza Yousefi |
Department of Surgery and Diagnostic Imaging, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran
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| نشانی اینترنتی |
http://beat.sums.ac.ir/article_44417_b7fe35128e763c624b62e940a177ce31.pdf |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/271/article-271-2060932.pdf |
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| زبان مقاله منتشر شده |
en |
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