این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Public Health، جلد ۴۸، شماره ۶، صفحات ۱۱۰۶-۱۱۱۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Adiponectin: An Indicator for Metabolic Syndrome
چکیده انگلیسی مقاله Abstract Background: Metabolic syndrome (MetS), a cluster of cardiometabolic risk factors, consider as a manifestation of obesity. However, a proportion of obese patients do not develop MetS. The aim of our study was to determine whether concentration of plasma adiponectin and leptin differ between metabolic unhealthy obese (MUO) patients and comparable age- and sex-matched control groups. Methods: In this case-control study, we assigned 51 obese patients with MetS (MUO) in cases group and 102 metabolic healthy obese (MHO) and normal weight metabolic healthy subjects matched for age and gender to cases in control groups. The study was conducted between December 2014 and February 2016 in the Endocrinology Research Center of Tehran University of Medical Sciences , Tehran , Iran.  We measured serum adiponectin, leptin, their ratio, and body composition in all subjects. Results: No significant differences were observed between MHO and MUO in term of total fat mass and trunk fat (P>0.05). Compared to MHO and normal weight metabolic healthy subjects, MUO subjects had lower levels of plasma adiponectin (P< 0.001) and lower plasma adiponectin to leptin ratio (P< 0.001) and a higher level of plasma leptin (P< 0.002). A Receiver Operator Characteristic curve was used to identify the ability of adiponectin and leptin level to predict the MetS. The area under the Receiver Operator Characteristic curve was 0.66 (P< 0.01), 0.73 (P< 0.001) and 0.75 (P< 0.001) for leptin, adiponectin, and adiponectin/leptin ratio levels respectively. Conclusion: Our study introduced adiponectin and leptin as indicator of MetS and obesity respectively.  
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله | Somaye YOSAEE
1. Department of Nutrition, School of Health, Larestan University of Medical Sciences, Larestan, Iran 2. Department of Nutrition, Emam Reza Teaching Hospital, Larestan University of Medical Sciences, Larestan, Iran


| Mahmoud KHODADOST
1. Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran 2. Gerash University of Medical Sciences, Gerash, Iran


| Alireza ESTEGHAMATI
Endocrinology and Metabolism Research Center (EMRC), Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran


| John R. SPEAKMAN
1. State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China 2. Institute of Biological and Environmental Sciences, University of Aberdeen, Scotland, UK


| Kurosh DJAFARIAN
Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, Tehran University of Medical Sciences, Tehran, Iran


| Vida BITARAFAN
Adelaide Medical School and National Health and Medical Research Council of Australia (NHMRC), Center of Research Ex-cellence in Translating Nutritional Science to Good Health, University of Adelaide, Adelaide, Australia


| Farzad SHIDFAR
Department of Nutritional Sciences, School of Public Health, Iran University of Medical Sciences, Tehran, Iran
نشانی اینترنتی http://ijph.tums.ac.ir/index.php/ijph/article/view/17349
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/86/article-86-1570434.pdf
کد مقاله (doi)
زبان مقاله منتشر شده
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات