این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Diabetes and Obesity، جلد ۱۰، شماره ۴، صفحات ۲۱۰-۲۱۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی The Effects of High Intensity Interval Training on HNF-4 α Gene Expression in Liver Tissue of Type 2 Diabetic Male Wistar Rats
چکیده انگلیسی مقاله Objective: This study examined the effect of high intensity interval training (HIIT) on HNF-4α gene expression, glucose and insulin in liver tissue of type 2 diabetic male Wistar rats. Materials and Methods: In this study, 20 male Wistar rats weighing 220 (±20) grams were selected. After type 2 diabetes (T2D) induction, the samples were divided into two groups of HIIT and control. The training program was 12 weeks and 5 times a week. Fasting glucose, serum insulin and HNF-4α gene expression in the liver tissue were measured in both groups after the last exercise session by using independent T-test. Results: The results showed that HIIT decreased significantly the fasting glucose (P-value: 0.001) and increased serum insulin (P-value: 0.001). Also, the expression of HNF-4α after HIIT significantly decreased in comparison to the control group (P-value: 0.003). Conclusion: Based on the findings, HIIT resulted in a significant decrease in fasting glucose and a significant increase in insulin that is likely to reduce the liver HNF-4α gene expression of T2D male Wistar rats by increasing serum insulin.  
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله | Elham Yadegari
PhD Student, Department of Exercise Physiology, South Tehran Branch, Islamic Azad University, Tehran, Iran.


| Abdol Ali Banaeifar
PhD, Department of Exercise Physiology, South Tehran Branch, Islamic Azad University, Tehran, Iran


| Mohamad Ali Azarbayjani
PhD, Department of Exercise Physiology, Central Tehran Branch, Islamic Azad University, Tehran, Iran


| Sajad Arshadi
PhD, Department of Exercise Physiology, South Tehran Branch, Islamic Azad University, Tehran, Iran
نشانی اینترنتی http://ijdo.ssu.ac.ir/browse.php?a_code=A-10-30-220&slc_lang=en&sid=1
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/213/article-213-1556914.pdf
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده تخصصی
نوع مقاله منتشر شده پژوهشی
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات