Veterinary Research Forum، جلد ۶، شماره ۳، صفحات ۲۲۷-۲۳۱

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عنوان انگلیسی The effect of the hexanic extracts of fig (Ficus carica) and olive (Olea europaea) fruit and nanoparticles of selenium on the immunogenicity of the inactivated avian influenza virus subtype H9N2
چکیده انگلیسی مقاله Influenza is a contagious viral disease that is seen in avian, human and other mammals, so its control is important. Vaccination against influenza virus subtype H9N2 is one of the ways in controlling program, for this reason several vaccines has been produced. Recently, application of inactivated oil-emulsion vaccines in poultry for controlling low pathogenic avian influenza is increasing. At present, oils that are used as adjuvant in commercial vaccines are mineral oils, which not only lack immunizing effect, but also produce some detriments. The aim of this study is the evaluation the immunogenicity of vegetable oils, which are more metabolizable and safer than mineral oils. In this study the efficacy of hexanic extracts of fig (Ficus carica) and olive (Olea europaea) fruit and also nano-selenium on the immunogenicity of the inactivated avian influenza virus subtype H9N2 was evaluated in broiler chickens. The results indicated that the prepared emulsions could elicit a little degree of immunity, but they could not inhibit the anamnestic response and infection. With regard to the results, it seems that the intact mixture of fig and olive fruit hexanic extracts could not be administered as an immunoadjuvant in the vaccine, and about nano-selenium. In spite of positive effect on the immunogenicity of avian influenza virus subtype H9N2, it still needs more work. 
کلیدواژه‌های انگلیسی مقاله Adjuvant,Avian influenza,Fig,Nano-selenium,Olive

نویسندگان مقاله امیرحسین اصل نجاری | amir hossein asl najjari
department of clinical sciences, faculty of veterinary medicine, university of tabriz, tabriz, iran
سازمان اصلی تایید شده: دانشگاه تبریز (Tabriz university)

ذوالفقار رجبی |
department of clinical sciences, faculty of veterinary medicine, university of tabriz, tabriz, iran
سازمان اصلی تایید شده: دانشگاه تبریز (Tabriz university)

مهدی وصفی مرندی | vasfi marandi
department of avian diseases, faculty of veterinary medicine, university of tehran, tehran, iran
سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

غلامرضا دهقان |
department of biology, faculty of sciences, university of tabriz, tabriz, iran
سازمان اصلی تایید شده: دانشگاه تبریز (Tabriz university)


نشانی اینترنتی http://vrf.iranjournals.ir/article_14310_2894a2326b5b67fdb46758895380cc80.pdf
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