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JCR 2016
جستجوی مقالات
پنجشنبه 16 بهمن 1404
Iranian Journal of Public Health
، جلد ۴۵، شماره ۴، صفحات ۴۳۵-۴۴۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژههای فارسی مقاله
عنوان انگلیسی
Predictive Role of Serum Tumor Markers in Diagnosis of Pulmo¬nary Tuberculosis
چکیده انگلیسی مقاله
Background: The diagnosis of pulmonary tuberculosis (PTB) is complicated and time-consuming currently. There was association of PTB with serum tumor markers. In this study we aimed to evaluate the predictive role of serum CA125, CA199 and CEA as diagnostic tools for PTB. Methods: This study was designed as a case-control study with 565 subjects who visited the Yijishan Hospital from Jun to Dec in 2014.This case-control study matched as for age and sex with 113 cases and 452 controls. Serum CA125, CA199 and CEA levels were detected by electrochemiluminescence instrument. The area under the curve (AUC) of the receiver operating characteristic (ROC) curve was performed to evaluate the diagnostic value on PTB. Results: Serum levels of CA125, CA199 and CEA in PTB patients were significantly higher than those in control group (P< 0.001). There was no significantly different of three tumor markers between initial treatment group and retreatment group. The logistic regression analysis showed that CA125 was an impact factor to PTB. The ROC analysis revealed that AUC of CA125 was 0.966 (95%CI: 0.951-0.981), the sensitivity, specificity in serum and cut-off were 95.6%, 85.0% and 10.30 U/ml, respectively. Conclusion: The serum CA125 has potential good diagnostic performance for PTB.
کلیدواژههای انگلیسی مقاله
نویسندگان مقاله
| Jingjing MA
Dept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China
| Dan XIA
Dept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China
| Jing HU
Dept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China
| Rui FU
Dept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China
| Lijun XU
Dept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China
| Ying ZHANG
Dept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China
| Mengying ZHANG
Dept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China
| Benhe LI
Dept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China
| Jianghua YANG
Dept. of Infectious Diseases, Yijishan Hospital, Wuhu City, China
| Yufeng WEN
Dept. of Preventive Medicine, School of Public Health, Wannan Medical College, Wuhu City, China
نشانی اینترنتی
http://ijph.tums.ac.ir/index.php/ijph/article/view/6573
فایل مقاله
اشکال در دسترسی به فایل - ./files/site1/rds_journals/86/article-86-1354418.pdf
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