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Iranian Journal of Public Health، جلد ۴۸، شماره ۱، صفحات ۱-۸

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عنوان انگلیسی The Association between Human Papillomavirus Infection and Smoking, Age, Gender in Lung Cancer Patients: A Meta-Analysis
چکیده انگلیسی مقاله Background: The aim of our study was to identify the association between Human papillomavirus (HPV) positive rate and smoking in lung cancer (LC) patients. Meanwhile, to analyze differences among gender, age differences on HPV infection rate in LC patients. Methods: We performed a systematic literature search through PubMed, Wan Fang, China National Knowledge Infrastructure (CNKI), MEDLINE, EMBASE (OVID), and Web of Science databases from 1991-2017, and we searched these keywords such as “lung cancer”, “HPV”, “smoking”, and “human papillomavirus”. Review Manager 5.3 software was used to analyze. An estimate of the odds ratio (OR) with 95% confidence intervals (CI) was calculated. Results: In China, a statistical significance was observed between HPV positive rate and smoking in LC patients (OR=2.34, 95%CI: 1.76–3.09, P< 0.001; I2 =25%). However, after stratified by region, no significance was observed in other regions, gender, and age. Conclusion: HPV infections are associated with smoking in LC patients. The association between HPV infection and smoking in LC patients may relate to different regions. There were no differences between gender and age among HPV infection rates in LC patients. To identify the etiology of smoking, HPV, and LC, a further experimental research needs to be conducted.  
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نویسندگان مقاله | Rui ZHANG
School of Public Health and Management, Research Center for Medicine and Social Development, Chongqing Medical University, Chongqing, 400016, China and Collaborative Innovation Center of Social Risk Governance in Health, Chongqing Medical University, Chongqing, 400016, China


| Ling CHEN
The Center of Experimental Teaching Management, Chongqing Medical University, Chongqing, 401331, China


| Ya-Deng CUI
School of Public Health and Management, Research Center for Medicine and Social Development, Chongqing Medical University, Chongqing, 400016, China and Collaborative Innovation Center of Social Risk Governance in Health, Chongqing Medical University, Chongqing, 400016, China


| Sungyung CHUN
Department of Football Science, School of Health Science, Honam University, Gwangju, Republic of Korea



نشانی اینترنتی http://ijph.tums.ac.ir/index.php/ijph/article/view/15933
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