این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Iranian Journal of Public Health، جلد ۴۸، شماره ۳، صفحات ۳۸۸-۳۹۹
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Cultured Epidermal Melanocyte Transplantation in Vitiligo: A Review Article
چکیده انگلیسی مقاله Abstract Background: The color of the skin is highly heritable but can be influenced by the environments and endocrine factors. Many other factors, sometimes destructive, are also involved in the formation of skin color, which sometimes affects pigmentation patterns. Vitiligo is an autoimmune hypopigmentation painless disorder with appearance of white patches and psychological effects on patients. It is a disease in which melanocytes of the skin are destroyed in certain areas; therefore depigmentation appears. Methods: We studied more than 60 articles. Several therapeutic methods have been used to return the color of skin in vitiligo. These methods include non-invasive treatment and surgical techniques. Among all these therapies, cell transplantation is an advanced procedure in regenerative medicine. Extraction of melanocytes from normal skin and then their cultivation in the laboratory provides a large number of these cells, the transplanting of which to depigmentation areas stimulates the site to irreversibly produce melanin. Results: The transplantation methods of these cells have been evolved over many years and the methods of producing blister have been changed to the injection of these cells to the target sites. Conclusion: In this review, autologous cultured melanocyte transplantation has been considered to be the most viable, safe, and effective method in the history of vitiligo treatments.    
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله | Shaghayegh ZOKAEI
School of Advanced Medical Sciences, Islamic Azad University, Tehran Medical Branch, Tehran, Iran


| Dariush D. FARHUD
1. School of Public Health, Tehran University of Medical Sciences, Tehran, Iran 2. Department of Basic Sciences, Iranian Academy of Medical Sciences, Tehran, Iran


| Mohammad KEYKHAEI
School of Medicine, Tehran University of Medical Sciences, Tehran, Iran


| Marjan ZARIF YEGANEH
Cellular and Molecular Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Hoda RAHIMI
Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran


| Hamideh MORAVVEJ
Skin Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
نشانی اینترنتی http://ijph.tums.ac.ir/index.php/ijph/article/view/16508
فایل مقاله اشکال در دسترسی به فایل - ./files/site1/rds_journals/86/article-86-1353995.pdf
کد مقاله (doi)
زبان مقاله منتشر شده
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات