| چکیده انگلیسی مقاله |
Background: Ketamine is the only anesthetic agent that leads to an increase of blood pressure and heart rate by activation of sympathetic nervous system. However, there is a controversy about this effect of ketamine especially if used in small dosage. We proposed to evaluate the hemodynamic effect of small dose of ketamine during Phacoemulsification. Methods: One hundred patients of ASA physical status I-III were chosen for this prospective, randomized, double-blind placebo-control study. Our patients were assigned randomly to two groups, ketamine group (n=50) and a control group (n=50). After premedication, 0.15 mg/kg ketamine was injected intravenously in ketamine group. After three minutes Phacoemulsification was begun under topical anesthesia. The hemodynamic variables were recorded during the procedure and compared between two groups. Results: The systolic, diastolic and mean blood pressure were statistically significantly higher in the ketamine group (p< 0.001) during the procedure. The heart rate during operation was higher in the ketamine group compared to control group (p< 0.001). 46 (92%) patients in the ketamine group and 38 (76%) patients in the control group were satisfied according to surgeons (p=0. 001). Nausea and vomiting occurred at similar rates in each group. Also, hallucination and other psychological events did not occur in either of the groups. Conclusion : We found that systolic, diastolic, mean arterial blood pressure in patients who received small dose of ketamine were higher during the operation. |
| نویسندگان مقاله |
مهدی صنعت کار | mehdi sanatkar
anesthesiology department, farabi hospital, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
مهران زارعی قنواتی | mehran zarei ganavati
ophthalmology department, farabi hospital, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
حسین صدرالسادات | hossein sadrossadat
anesthesiology department, farabi hospital, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
مهرداد shoroughi | mehrdad shoroughi
anesthesiology department, farabi hospital, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
عبدالحسین بهبهانی | abdolhossein behbahani
anesthesiology department, farabi hospital, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
علیرضا ابراهیم سلطانی | alireza ebrahim soltani
anesthesiology department, farabi hospital, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
مهرداد گودرزی | mehrdad goudarzi
anesthesiology department, farabi hospital, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
عباس استاد علیپور | abbas ostad alipour
anesthesiology department, farabi hospital, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
آناهید ملکی | anahid maleki
anesthesiology department, farabi hospital, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
ابراهیم اسپهبدی | ebrahim espahbodi
anesthesiology department, farabi hospital, tehran university of medical sciences, tehran, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
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