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Archives of Anesthesiology and Critical Care، جلد ۱، شماره ۱، صفحات ۳-۷
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| چکیده فارسی مقاله |
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| عنوان انگلیسی |
Comparison of Plasma Viscosity Following Administration of Albumin 5% in Half-Normal Saline versus Normal Saline during Minor Surgeries |
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| چکیده انگلیسی مقاله |
Background: We aimed to compare the effect of albumin 5% in half normal saline (half NS) versus normal saline (NS) infusion on the plasma viscosity in the near-normal physiological condition. According to the high oncotic pressure of albumin along with prolonged half-life of its molecules in comparison to NS in the intra-vascular compartment, it has been proposed that a more significant reduction of the plasma viscosity might be expected after the infusion of albumin. Methods: A total of 56 patients referring to the general operating room for their elective minor surgeries were evenly divided into two groups (V1, V2). It was calculated that 28 patients were needed to be enroll in each study group to detect a difference as big as 0.15 millipoise (mPa.s) with a statistical power of 80%. The V1 group received 1000 ml of NS but the V2 group received 1000 ml of recombinant albumin 5% in half NS within one hour, as fluid replacement therapy, during the intra-operative period. We have designed a simple measurement system according to Poiseuille’s formula by which the viscosity value could be measured reliably since the system was calibrated frequently using distilled water as a reference. Results: The mean value of the pre-operative plasma viscosity of the patients was 1. 73 ± 0.25 mPa.s and 1.76 ± 0.21 mPa.s in V1 and V2 groups respectively. After the infusion of the fluids, the mean viscosity values decreased to 1. 68 ± 0.30 mPa.s and 1.66 ± 0.17mPa.s in V1 and V2 groups respectively (p= 0.37). |
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| نویسندگان مقاله |
اتابک نجفی | atabak najafi
tehran university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
مژده جلالی | mozhde jalali
tehran university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
فرهاد اعتضادی | farhad etezadi
tehran university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
محمد رضا خواجوی | mohammad reza khajavi
tehran university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
رضا شریعت محرری | reza shariat moharari
tehran university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
فرساد ایمانی | farsad imani
tehran university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
پیمان پورفخر | peiman pourfakhr
tehran university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
مجتبی مجتهدزاده | mojtaba mojtahedzadeh
tehran university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)
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| نشانی اینترنتی |
http://aacc.tums.ac.ir/index.php/aacc/article/view/5 |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
Research Article(s) |
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