Archives of Anesthesiology and Critical Care، جلد ۱، شماره ۳، صفحات ۸۰-۸۳

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عنوان انگلیسی Use of Chloral Hydrate as a Sedative Agent before General Anesthesia in Pediatric Population Undergoing Eye Examination
چکیده انگلیسی مقاله Background: Chloral hydrate (CH) is a sedative agent that is widely used in infants and children for several decades. The purpose of this study was to evaluate the safety and efficacy of CH before general anesthesia in pediatric population undergoing eye examination. Methods: 165 pediatric patients with retinal tumor were examined from December 2014 to May 2015. 158 (95.7%) children were sedated by CH before general anesthesia. CH was used at a dose of 25 mg/kg with an augmentation dose, if necessary, in 20-30 minutes. We recorded the safety of CH, the success or fail of sedation, augmentation CH dose, time to sedation and complications of CH administration. Results: In our study 158 (95.7%) children were sedated by CH and sixty four (40.5%) of these patients were under one year of age and ninety four (59.5%) were older. Successful sedation was achieved in 150/158 (94.9%) of the children. The success rate of sedation was higher in children below 1 year of age (63/64; 98.4%) compared to subjects older than 1 year (88/94; 93.6%) (P=0.01). The mean of time to sedation was 20.8±12.4 and 22.4±14.8 minutes in children below 1 year of age and older than 1 year respectively (p=0.91). Complications were observed in 4/158 (2.5%) of the children. We observed no episodes of desaturation after administration of CH in all subjects. Conclusion: CH is a safe and effective sedative agent for children before general anesthesia provided it is used in a hospital setting with appropriately trained staff. 
کلیدواژه‌های انگلیسی مقاله chloral hydrate,pediatrics,sedation,general anesthesia

نویسندگان مقاله مهدی صنعت کار | mehdi sanatkar
from the department of anesthesiology and critical care, farabi hospital, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

فریبا قاسمی | fariba ghassemi
department of ophthalmology, farabi hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

علیرضا خدابنده | alireza khodabande
department of ophthalmology, farabi hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

حسین صدرالسادات | hossein sadrossadat
from the department of anesthesiology and critical care, farabi hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

ابراهیم اسپهبدی | ebrahim espahbodi
from the department of anesthesiology and critical care, farabi hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

مهرداد shoroughi | mehrdad shoroughi
from the department of anesthesiology and critical care, farabi hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

علیرضا ابراهیم سلطانی | alireza ebrahim soltani
from the department of anesthesiology and critical care, farabi hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

جلیل مکارم | jalil makarem
from the department of anesthesiology and critical care, farabi hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

مهرداد گودرزی | mehrdad goudarzi
from the department of anesthesiology and critical care, farabi hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

امیر عباس یاقوتی | amir abbas yaghooti
from the department of anesthesiology and critical care, farabi hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

میهن جعفری جاوید | mihan jafari javid
from the department of anesthesiology and critical care, farabi hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

آناهید ملکی | anahid maleki
fromthedepartmentofanesthesiology and critical care, farabi hospital, tehran university of medical sciences, tehran, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)


نشانی اینترنتی http://aacc.tums.ac.ir/index.php/aacc/article/view/6
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