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Journal of Medical Bacteriology، جلد ۲، شماره ۱-۲، صفحات ۱۲-۱۹
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عنوان انگلیسی The Frequency of Extended Spectrum Beta Lactamase (ESBL) in Escherichia coli and Klebsiella pneumoniae: A Report from Mashhad, Iran
چکیده انگلیسی مقاله B ackground: In recent decades, extended spectrum beta-lactamase (ESBL) producing bacteria have increased worldwide. The most important causative agents of nosocomial infections throughout the world, Escherichia coli and Klebsiella pneumoniae as main ESBL-producing bacteria are so highly regarded. Trends in the treatment of infections by such bacteria have led to a global concern. This study was conducted to evaluate the incidence of ESBL producing E. coli and K. pneumoniae among inpatients and outpatients referred to the Imam Reza hospital unit in Mashhad during 2007-8. Methods: This study represents a descriptive cross-sectional study. All 339 samples from hospital and a special clinic of the Imam Reza hospital of Mashhad were collected and cultured in defined media. Identification by morphological and biochemical tests were performed to determine the Enterobacteriaceae genera. The secretion of ESBL was studied by the double disc diffusion method. At the end, the data were analyzed by statistical software. R esults: Out of 339 isolates collected from 192 women (56.6%) and 147 men (43.4%), 26.5% of E. coli (n = 211) and 43% of K. pneumoniae (n = 128) were ESBL positive. Most of the ESBL-positive isolates were related to ICU and the least of them were related to neonatal ward. C onclusion: The present study indicates the high prevalence of ESBL producing E nterobacteriaceae family especially in inpatients. Limiting the spread of such superbugs is of utmost importance.
کلیدواژه‌های انگلیسی مقاله Escherichia coli, Klebsiella pneumoniae, Beta-Lactamases
نویسندگان مقاله فاطمه اشرفیان | fatemeh ashrafian
department of medical microbiology, faculty of medicine, shahid beheshti university of medical sciences, tehran, ir iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

عمران عسکری | emran askari
mashhad medical microbiology student research group, mashhad university of medical sciences, department of medical bacteriology and virology, imam reza hospital, mashhad, ir iran and student research committee, faculty of medicine, mashhad university of medical sciences, mashhad, ir iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

الناز kalamatizade | elnaz kalamatizade
mashhad medical microbiology student research group, mashhad university of medical sciences, department of medical bacteriology and virology, imam reza hospital, mashhad, ir iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

محمدجواد قبولی شاهرودی | mohammadjavad ghabouli shahroodi
department of infectious diseases, mashhad university of medical sciences, mashhad, ir iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

محبوبه نادری نسب | mahboubeh naderi nasab
mashhad medical microbiology student research group, mashhad university of medical sciences, department of medical bacteriology and virology, imam reza hospital, mashhad, ir iran and faculty of medicine, mashhad university of medical sciences, mashhad, ir iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

نشانی اینترنتی http://jmb.tums.ac.ir/index.php/jmb/article/view/34
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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