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Asia Pacific Journal of Medical Toxicology، جلد ۲، شماره ۴، صفحات ۱۵۳-۱۵۶
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Coma Blisters in the Setting of Quetiapine Overdose: Case Report and Review of Literature |
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| چکیده انگلیسی مقاله |
Background: Skin lesions and blistering in the overdose patient, most notably associated with barbiturate overdoses, are commonly referred to as coma blisters, 'barb blisters', or 'barb burns'. We present a patient who was noted to have skin lesions including bullae and blistering following a prolonged coma after quetiapine overdose. Case report: A 27 year old male presented to our institution with the history of having ingested 7,200 mg of quetiapine in a suicide attempt up to 35 hours prior to being discovered. The patient was found comatose, and was noted to have multiple vesicles on his right ankle and a firm, erythematous plaque and bullae on his right thigh. Discussion: Sequelae related to prolonged immobility of any cause may include injury to muscle, vascular, microvascular and cutaneous structures. Coma blisters differ from pressure ulcers in many ways and cannot be graded using the typical staging system. Histopathologic analysis suggests an array of microvascular injuries which are secondary to direct pressure injury as well as specific drug effect. Conclusion: This is the first description of a dermatologic manifestation attributed to coma from isolated quetiapine overdose. Blister formation can be considered as a possible complication of quetiapine overdose. How to cite this article: Wiegand TJ, Gorodetsky RM, Peredy TR. Coma Blisters in the Setting of Quetiapine Overdose: Case Report and Review of Literature. Asia Pac J Med Toxicol 2013;2:153-6. |
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| کلیدواژه‌های انگلیسی مقاله |
Blister, Coma, Quetiapine, Overdose |
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| نویسندگان مقاله |
timothy wiegand | timothy wiegand
university of rochester medical center , strong memorial hospital, rochester, usa
راشل gorodetsky | rachel gorodetsky
university of rochester medical center , strong memorial hospital, rochester, usa.department of pharmacy practice, d’youville college school of pharmacy, buffalo, usa
tamas peredy | tamas peredy
maine medical center, university of southern maine, portland, usa.northern new england poison center, portland, usa
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| نشانی اینترنتی |
http://apjmt.mums.ac.ir/article_2040.html |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
2 |
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