این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Avicenna Journal of Phytomedicine، جلد ۴، شماره ۳، صفحات ۲۱۵-۲۲۴
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Preliminary pharmacological activity of the methanolic extract of Premna integrifolia barks in rats
چکیده انگلیسی مقاله Objective: Premna integrifolia Linn (Family: Verbenaceae) synonym of Premna serratifolia has tremendous medicinal value. Preliminary pharmacological studies were performed on the methanolic extract of Premna integrifolia (MEPI) bark to investigate neuropharmacological, analgesic, and anti-inflammatory activities. Materials and methods: Neuropharmacology study was done by open field and hole cross test whereas acetic acid writhing test and formalin induced pain was done for analgesic activity of MEPI. Carrageenan induced inflammatory model was considered for anti-inflammatory activity evaluation. Results: A statistically significant (p< 0.05) decrease in locomotor activity was observed at all doses in the open-field and hole-cross tests. The extract significantly (p< 0.05) and dose dependently reduced the writhing reflex in the acetic acid-induced writhing test as well as licking response in the formalin induced inflammatory pain. At 200 mg/kg body weight dose, MEPI showed 71.16% inhibition in carrageenan induced anti-inflammatory activity. Conclusion: The finding of this study suggests that MEPI will provide scientific support for the use of this species in traditional medicine.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله hajera خاتون | hajera khatun
department of pharmacy, southeast university, dhaka, bangladesh


rajib majumder | rajib majumder
department of pharmacy, atish dipankar university of science and technology, dhaka, bangladesh


efte kharul عالم | efte kharul alam
department of pharmacy, atish dipankar university of science and technology, dhaka, bangladesh


al mamun | al mamun
department of pharmacy, rajshahi university, rajshahi, bangladesh


safkath ibne جامی | safkath ibne jami
department of pharmacy, university of asia pacific, dhaka, bangladesh


بدرول عالم | badrul alam
department of pharmacy, jahangirnagar university, savar, dhaka, bangladesh
نشانی اینترنتی http://ajp.mums.ac.ir/article_2331.html
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Research Article
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات