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Avicenna Journal of Phytomedicine، جلد ۵، شماره ۱، صفحات ۶۹-۷۷
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عنوان انگلیسی Anti-inflammatory, Analgesic and Antiulcer properties of Porphyra vietnamensis
چکیده انگلیسی مقاله Objectives: Aim of the present work was to investigate the anti-inflammatory, analgesic and antiulcer effects of red seaweed Porphyra vietnamensis (P. vietnamenis). Materials and Methods: Aqueous (POR) and alcoholic (PE) fractions were successfully isolated from P. vietnamenis. Further biological investigations were performed using a classic test of paw edema induced by carrageenan, writhing induced by acetic acid, hot plate method and naproxen induced gastro-duodenal ulcer. Results: Among the fractions POR showed better activity. POR and PE significantly (p < 0.05) reduced carrageenan induced paw edema in a dose dependent manner. In the writhing test POR significantly (p < 0.05) reduced abdominal writhes than PE. In hot plate method POR showed better analgesic activity than PE. POR showed comparable ulcers reducing potential (p< 0.01) to that of omeprazole, and has more ulcer reducing potential then PE. Conclusions: The results of this study demonstrated that P. vietnamenis aqueous fraction possesses biological activity that is close to the standards taken for the treatment of peripheral painful or/and inflammatory and ulcer conditions.
کلیدواژه‌های انگلیسی مقاله Porphyra, Porphyran, Carrageenan, analgesia, Ulcer
نویسندگان مقاله saurabh بهاتیا | saurabh bhatia
dm college of pharmacy, bahadurgah, haryana, india.


kiran شارما | kiran sharma
deptt. of pharmaceutical sciences, jamia hamdard, new delhi, india.


ajay شارما | ajay sharma
seoul national university, republic of korea, korea.


kalpana nagpal | kalpana nagpal
division of pharmaceutics, faculty of medical sciences, lovely professional university, phagwara, punjab india.


tanmoy bers | tanmoy bers
department of pharmaceutical technology, jadavpur university, kolkata, india.
نشانی اینترنتی http://ajp.mums.ac.ir/article_3758.html
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Research Article
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