Iranian Journal of Neonatology، جلد ۴، شماره ۳، صفحات ۲۰-۲۵
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Effect of clofibrate on serum triglyceride and cholesterol after intravenous lipid in very low birth weight neonates
چکیده انگلیسی مقاله Background Lipoprotein lipase activity can be increased by clofibrate. Clofibrate is used to reduce serum triglyceride level in adults. The aim of this study was to determine the effect of clofibrate on serum triglyceride and cholesterol level after administration of intravenous lipid in very low birth weight neonates. Method In a randomized double blind placebo – controlled study, 60 very low birth weight neonates were elected. They received intravenous lipid for parental nutrition. Study participants (case) received one dose clofibrate 100 mg/kg orally. Control group received sterile water for placebo as volume as clofibrate. Serum triglyceride and cholesterol levels were measured in first and fifth days after starting of intravenous lipid (one day after intervention). Results Two groups were the same in sex, birth weight, gestational age and mode of delivery. There were no significant difference between the clofibrate and control groups in mean total serum triglyceride and cholesterol levels at before and after drugs administration (P=0.20 and 0.40 respectively). Conclusion This study showed although clofibrate has been reduced serum triglyceride levels in adults but it has not effect on serum triglyceride and cholesterol levels in very low birth weight neonates who use intravenous lipid.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله a محمدزاده | a mohammadzadeh
neonatal research center, imam reza hospital, faculty of medicine, mashhad university of medical sciences, mashad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

as فرهت | as farhat
neonatal research center, imam reza hospital, faculty of medicine, mashhad university of medical sciences, mashad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

h اسماعیلی | h esmaeli
biostatistics ph.d. associated professor, neonatal research center, faculty of medicine, mashhad university of medical sciences, mashad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

r امیری | r amiri
master of pediatric nursing, faculty of nursing and midwifery, mashhad university of medical sciences, mashad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

نشانی اینترنتی http://ijn.mums.ac.ir/article_1749.html
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده تحقیقی اصیل
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات