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Iranian Journal of Neonatology، جلد ۴، شماره ۴، صفحات ۳۹-۵۱
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Neonatal Sepsis: An Update |
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| چکیده انگلیسی مقاله |
Sepsis is the most common cause of neonatal mortality. As per National Neonatal-Perinatal Database (NNPD), 2002-2003, the incidence of neonatal sepsis in India was 30 per 1000 live births. Signs and symptoms of sepsis are nonspecific; therefore empirical antimicrobial therapy is promptly initiated after obtaining appropriate cultures. The early manifestations of neonatal sepsis are vague and ill-defined. Novel approaches in the diagnosis of neonatal sepsis include heart rate analysis on ECG, and colorimetric analysis of skin color. Although blood culture is the gold standard for the diagnosis of sepsis, culture reports are available only after 48-72 hours. In this era of multidrug resistance, it is mandatory to avoid unnecessary use of antibiotics to treat non-infected infants. Thus, rapid diagnostic test(s) that include Interleukien-6 (IL-6), neutrophil CD64 index, procalcitonin and nucleated RBC count– and differentiate the infected infants from the non-infected, particularly in the early neonatal period– have the potential to make a significant impact on neonatal care. The aim of this review is to specify the diagnostic criteria, treatment guidelines, and a summary of recent diagnostic tests of sepsis, along with the preventive measures. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
anjali کله | anjali kale
department of pediatrics , mahatma gandhi mission hospital aurangabad, 431001, aurangabad, india
deepali jaybhaye | deepali jaybhaye
department of pharmacology, mahatma gandhi mission hospital aurangabad, 431001, aurangabad, india
پ سینگ bonde | vijay bonde
department of pharmacology, mahatma gandhi mission hospital aurangabad, 431001, aurangabad, india
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| نشانی اینترنتی |
http://ijn.mums.ac.ir/article_2012.html |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
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