Iranian Journal of Neonatology، جلد ۷، شماره ۲، صفحات ۴۰-۴۳

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عنوان انگلیسی Neonatal Effects of Substance Abuse during Pregnancy
چکیده انگلیسی مقاله Drug abuse in pregnancy is not uncommon, and the use of illicit opioids during pregnancy is associated with an increased risk of adverse outcomes. The aim of the study was to assess neonatal outcome of pregnancy with maternal addiction. Materials and Methods: In this cohort study we assessed 100 pregnant women 15 -49 years old. To identify drug exposure was used self- questionnaire (Self-Report). Data on pregnancies complicated by illicit drug abuse (n = 50) were collected during a 2-year period (2014 - 2016) at Hospitals affiliated to Mashhad University of medical sciences. Data on the type of drug, course of gestation and labor, and on neonatal complications outcome were considered. Medical records on all non-dependence pregnancies during the study period were used as a non-exposed group (n = 50).To control possible confounding factor was used of multiple logistic regression model. Results: our results showed The risk of various congenital anomalies was 5-fold in the group of children born to addicted mothers (RR = 5.65, 95% CI: 0.27-114.7). Also RDS (RR=5.1, 95% CI: 1.16-22.3), meconial amniotic fluid (RR=2.26, 95% CI: 0.21-24.1), NICU admission (RR=3.07, 95% CI: 1.93-4.88), neonatal seizure (RR=5.38, 95%CI: 1.97-14.64), neonatal hypoglycemia (RR=2.26, 95% CI: 0.60-8.54) were significantly more common in the group of pregnant addicts. Conclusion: Addiction pregnancies must be considered as high-risk pregnancies according to perinatal outcome. We should prepare Appropriate obstetric and neonatal care in these pregnancies. 
کلیدواژه‌های انگلیسی مقاله substance abuse, Pregnancy outcome, neonatal outcome

نویسندگان مقاله رضا سعیدی | reza saeidi
associated professor of neonatology, neonatal research center, imam reza hospital, faculty of medicine, mashhad university of medical sciences, mashhad, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

احسان موسی فرخانی | ehsan mosa farkhani
phd candidate in epidemiology, mashhad university of medical sciences, mashhad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

مریم سعیدی | maryam saeidi
bsc in midwifery, mashhad university of medical sciences, mashhad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

شکوفه ایزدی | shokufeh izadi
general physician, mashhad university of medical sciences, mashhad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)

مریم زیادی لطف آبادی | maryam ziadi lotfabadi
department of health, md-mph,mashhad university of medical sciences, mashhad, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (Mashhad university of medical sciences)


نشانی اینترنتی http://ijn.mums.ac.ir/article_7265.html
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