این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Journal of Research in Medical Sciences، جلد ۱۲، شماره ۵، صفحات ۲۴۶-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Comparison of effects of thiopental, propofol or ketamine on the cardiovascular responses of the oculocardiac reflex during strabismus surgery
چکیده انگلیسی مقاله BACKGROUND : The oculocardiac reflex (OCR), which is most often encountered during strabismus surgery in children, may cause bradycardia, arrhythmias and cardiac arrest following a variety of stimuli arising in or near the eyeball. The main purpose of this study was to evaluate the effects of various anesthetic regimens on modulation of the cardiovascular effects of the OCR during strabismus surgery. METHODS : Three hundred ASA physical status I-II patients, scheduled for elective strabismus surgery under general anesthesia, randomly allocated in a double blind fashion to one of the three anesthetic regimens: group P: propofol (2 mg/kg), alfentanil 0.02 mg/kg and atracurium 0.5 mg/kg at induction; group K: ketamine racemate (2 mg/kg), alfentanil 0.02 mg/kg and atracurium 0.5 mg/kg at induction; group T: thiopental (5 mg/kg), alfentanil 0.02 mg/kg, and atracurium 0.5 mg/kg at induction. Mean arterial pressure (MAP) and heart rate (HR) were recorded just before induction, at 1, 15, 30, 45 and 60 minutes after induction. OCR was defined as a 20 beats/minute change in HR induced by traction compared with basal value. RESULTS : Mean HR (± SD) during total period of surgery in group P was significantly slower than that in group K (111.90 ± 1.10 vs. 116.7 ± 0.70, respectively; P< 0.05). Mean HR changes (± SD) in group K was significantly higher than that in group P (11.2 ± 1.44 vs. 8.7 ± 1.50 respectively, P< 0.05). MAP changes (± SD) was significantly lower in patients in group P compared with patients in group K or T (12.5 ± 1.13 vs. 19.3 ± 0.80 or 18.9 ± 0.91, respectively; P< 0.05). Incidence of OCR was significantly lower in patients in group K compared with patients in group T or P (9% vs. 16% and 13%. Respectively; P< 0.05). CONCLUSIONS: Induction of anesthesia with ketamine is associated with the least cardiovascular changes induced by OCR during strabismus surgery. KEY WORDS : Oculocardiac reflex, strabismus surgery, ketamine, propofol, thiopental.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله محمد رضا صفوی | mohammad reza safavi
department of anesthesiology, isfahan university of medical sciences, isfahan, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

عظیم هنرمند | azim honarmand
department of anesthesiology, isfahan university of medical sciences, isfahan, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/1122
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Articles
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات