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Journal of Research in Medical Sciences، جلد ۱۷، شماره ۳، صفحات ۰-۰

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عنوان انگلیسی Color blindness among multiple sclerosis patients in Isfahan
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE FA MicrosoftInternetExplorer4 BACKGROUND : Multiple sclerosis (MS) is a disease of young and middle aged individuals with a demyelinative axonal damage nature in central nervous system that causes various signs and symptoms. As color vision needs normal function of optic nerve and macula, it is proposed that MS can alter it via influencing optic nerve. In this survey, we evaluated color vision abnormalities and its relationship with history of optic neuritis and abnormal visual evoked potentials (VEPs) among MS patients. METHODS : The case group was included of clinically definitive MS patients and the same number of normal population was enrolled as the control group. Color vision of all the participants was evaluated by Ishihara test and then visual evoked potential (VEPs) and history of optic neuritis (ON) was assessed among them. Then, frequency of color blindness was compared between the case and the control group. Finally, color blinded patients were compared to those with the history of ON and abnormal VEPs. RESULTS : 63 MS patients and the same number of normal populations were enrolled in this study. 12 patients had color blindness based on the Ishihara test; only 3 of them were among the control group, which showed a significant different between the two groups ( P = 0.013). There was a significant relationship between the color blindness and abnormal VEP ( R = 0.53, P = 0.023) but not for the color blindness and ON ( P = 0.67). CONCLUSIONS : This study demonstrates a significant correlation between color blindness and multiple sclerosis including ones with abnormal prolonged VEP latencies. Therefore, in individuals with acquired color vision impairment, an evaluation for potentially serious underlying diseases like MS is essential. KEYWORDS : Multiple sclerosis, color blindness, VEP, Ishihara test, optic neuritis
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نویسندگان مقاله وحید شایگان نژاد | vahid shaygannejad
department of neurology, isfahan neuroscience research center, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

خدایار گلابچی | khodayar golabchi
student of medicine, isfahan neuroscience research center, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

علیرضا دهقانی | alireza dehghani
department of ophtalmology, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

فرشته اشتری | fereshteh ashtari
department of neurology, isfahan neuroscience research center, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

سپهر حقیقی | sepehr haghighi
student of medicine, student research committee, isfahan neuroscience research center, isfahan university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

مهسا میرزنده دل | mahsa mirzendehdel
student of medicine, student research committee, isfahan neuroscience research center, isfahan university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

مجید قاسمی | majid ghasemi
department of neurology, isfahan neuroscience research center, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/7003
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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