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Journal of Research in Medical Sciences، جلد ۱۷، شماره ۳، صفحات ۰-۰
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عنوان انگلیسی Pattern of brain blood perfusion in tinnitus patients using technetium-99m SPECT imaging
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE FA MicrosoftInternetExplorer4 BACKGROUND: Tinnitus is associated with an increased activity in central auditory system as demonstrated by neuroimaging studies. Brain perfusion scanning using single photon emission computed tomography (SPECT) was done to understand the pattern of brain blood perfusion of tinnitus subjects and find the areas which are mostly abnormal in these patients. METHODS: A number of 122 patients with tinnitus were enrolled to this cross-sectional study. They underwent SPECT and magnetic resonance imaging (MRI) of brain, and the images were fused to find the regions with abnormal perfusion. RESULTS: SPECT scan results were abnormal in 101 patients (83%). Most patients had bilateral abnormal perfusion ( N = 65, 53.3%), and most subjects had abnormality in middle-temporal gyrus ( N = 83, 68%) and temporoparietal cortex ( N = 46, 37.7%). Patients with multifocal involvement had the least mean age than other 2 groups (patients with no abnormality and unifocal abnormality) ( P value = 0.045). CONCLUSION: Brain blood perfusion pattern differs in patient with tinnitus than others. These patients have brain perfusion abnormality, mostly in auditory gyrus (middle temporal) and associative cortex (temporoparietal cortex). Multifocal abnormalities might be due to more cognitive and emotional brain centers involvement due to tinnitus or more stress and anxiety of tinnitus in the young patients.
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نویسندگان مقاله سعید محمودیان | saeid mahmoudian
otorhinolaryngology department, hannover medical university mhh and center for systems neuroscience hannover, university of veterinary medicine hannover, fundation, hannover, germany, ent and head amp;amp; neck research center, tehran university of medical sci

سازمان اصلی تایید شده: دانشگاه تهران (Tehran university)

محمد فرهادی | mohammad farhadi
ent and head amp;amp; neck research center, rasoul-e-akram hospital, tehran university of medical sciences and iran national science foundation insf , tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

سعید غلامی | saeid gholami
firoozgar clinical research development center, firoozgar hospital, tehran university of medical sciences, tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

فریبا سدادی | fariba saddadi
agriculture, medical amp;amp; industrial research school, tehran, iran


علی رضا کریمیان | ali reza karimian
faculty of engineering and biomedical engineering, the university of isfahan, isfahan, iran

سازمان اصلی تایید شده: دانشگاه اصفهان (Isfahan university)

میرزایی | mohammad mirzaei
agriculture, medical amp;amp; industrial research school, tehran, ira


اسماعیل قریشی | esmaeel ghoreyshi
department of neurology, tehran university of medical sciences tehran, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی تهران (Tehran university of medical sciences)

مجید احمدی زاده | majid ahmadizadeh
pars general hospital, department of otolaryngology, head amp;amp; neck surgery,tehran, iran


توماس lenarz | thomas lenarz
otorhinolaryngology department, hannover medical university mhh and center for systems neuroscience hannover, university of veterinary medicine hannover, fundation, hannover, germany
نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/6983
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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