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Journal of Research in Medical Sciences، جلد ۱۷، شماره ۳، صفحات ۰-۰

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عنوان انگلیسی Bowenoid transformation in seborrheic keratosis: A retrospective analysis of 429 patients
چکیده انگلیسی مقاله BACKGROUND : Seborrheic keratosis is a common, benign skin tumor. Numerous reports have shown its possibility of malignant transformation. This study was designed to demonstrate the occurrence of concomitant seborrheic keratosis and skin cancers. METHODS : Data was retrospectively reviewed from all patients with a diagnosis of seborrheic keratosis in pathology department of Alzahra Hospital and a private pathology laboratory in Isfahan, Iran over a 4-year period. We classified all demographic data and associated dysplasia or Bowen's disease and analyzed them by student-t or chi-square tests. RESULTS : From all 429 specimens, 5 (1.2%) were found to be associated with Bowen's disease and one (0.2%) with mild dysplasia in squamous epithelium . All cases arose within the clinically, atypical seborrheic keratosis. More men were affected with lesions alone and with malignancy (230/423 (54.4%) and 5/6 (83.3%), respectively) compared to women. The average age of patients suffering from lesions with and without associated malignancy was 57 and 54 years, respectively. The common site of lesion alone was head and neck but lesions with malignancy involved lower extremities. The two lesions were significantly different in site of occurrence (p < 0.001). CONCLUSIONS : Generally, although the association between seborrheic keratosis and skin malignancy appears to be accidental, it must always be in mind. Therefore, histopathologic examination of all seborrheic keratosis should be considered, especially when seborrheic keratosis has atypical clinical manifestations. KEYWORDS : Keratosis Seborrheic, Bowen's Disease, Dysplasia
کلیدواژه‌های انگلیسی مقاله keratosis Seborrheic, Bowen&,#039,s disease

نویسندگان مقاله پروین رجبی | parvin rajabi
professor, department of pathology, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

ندا ادیبی | neda adibi
assistant professor, psychosomatic research center, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

پردیس نعمت الهی | pardis nematolahi
assistant professor, department of pathology, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

میترا حیدرپور | mitra heidarpour
associated professor, department of pathology, school of medicine , isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

مهدی افتخاری | mehdi eftekhari
resident, department of pathology, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

امیر حسین سیادت | amir hossein siadat
assistant professor, department of dermatology, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/7508
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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