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Journal of Research in Medical Sciences، جلد ۱۷، شماره ۰۳، صفحات ۰-۰
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عنوان انگلیسی Different measurements of the obesity, adiponectin and coronary heart disease: a single-center study from Isfahan
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA Background: Adipose tissue as an endocrine organ secretes adiponectin that is a cardiovascular atherosclerosis-modulating factor. However, some studies showed that adiponectin reduces obesity. In the present study, adiponectin association with body mass index (BMI), waist circumference (WC), visceral adipose tissue (VAT) and subcutaneous visceral tissue (SAT) as different measurements of obesity were evaluated in patients with coronary heart disease (CHD). Materials and Methods: Sixty-eight patients with CHD were chosen using simple random sampling. Body weight, height, WC and blood pressure were measured. Fasting blood samples were taken to assess fasting blood sugar , total cholesterol, triglyceride, low and high-density lipoproteins cholesterol. Patients underwent an abdominal computerized scan (CTS) to detect VAT and SAT. Linear regression test used to assess the relation of different measurements of the obesity with adiponectin adjusting for age, sex, hypertension , dyslipidemia, and diabetes mellitus. Results: The mean age of the study population was 50.5 ± 7.0. Females were 67.6% of study population. Multivariate analyses showed the inverse association of waist-to-height ratio (WHtR) (β = -0.25, p = 0.03), WC (β = -0.24, p = 0.24) and visceral fat (β = -0.32, p = 0.01) with adiponectin. Conclusions: WC and WHtR are simple proxy measures of obesity that better showed adverse metabolic effect of visceral fat in patients with CHD . Key Words: Adiponectin, Coronary Heart Disease, Obesity, Intra-abdominal Fat, Waist Circumference, Waist-to-height Ratio
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نویسندگان مقاله زهرا پورمقدس | zahra pourmoghaddas
assistant researcher, cardiovascular research center, isfahan cardiovascular research institute, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

معصومه صادقی | masoumeh sadeghi
associate professor, cardiac rehabilitation research center, isfahan cardiovascular research institute, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

علی حکمت نیا | ali hekmatnia
assistant professor, department of radiology, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

حمید صانعی | hamid sanei
assistant professor, department of cardiology, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

بابک توکلی | babak tavakoli
resident, department of radiology, student research committee, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

حمیدرضا روح افزا | hamidreza roohafza
psychiatrist, cardiovascular research center, isfahan cardiovascular research institute, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نضال صراف زادگان | nizal sarrafzadegan
professor, cardiovascular research center, isfahan cardiovascular research institute, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/7521
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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