این سایت در حال حاضر پشتیبانی نمی شود و امکان دارد داده های نشریات بروز نباشند
Journal of Research in Medical Sciences، جلد ۱۷، شماره ۵، صفحات ۰-۰
عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله
عنوان انگلیسی Intravenous pamidronate for refractory rheumatoid arthritis
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE FA MicrosoftInternetExplorer4 BACKGROUND: Atherosclerosis is the leading cause of death in hemodialysis patients. These patients are also highly prone to L-carnitine deficiency due to kidney disease. In this clinical trial, we investigated the effect of oral L-carnitine on the endothelial function of these patients. METHODS: We studied 31 adult chronic hemodialysis patients in our center and divided them into two groups, a group of 20 patients who received 1500 mg/dialysis interval (every other day) oral L-carnitine and a control group of 11 patients who received placebo for one month. Ultrasonographic measurement of flow mediated dilation and carotid intima media thickness were performed before and after one month of L-carnitine and Placebo therapy. RESULTS: This study showed that after one month of L-carnitine or placebo therapy there was no significant improvement in flow mediated dilation ( p = 0.80, p=0.59 respectively) or decrease in carotid intima media thickness ( p = 0.12, p = 0.50 respectively). CONCLUSIONS: Our study revealed that one month oral L-carnitine therapy does not improve endothelial function in hemodialysis patients. Long term studies with a large sample size using intravenous form and higher doses of the drug are required to clarify the questionable role of L-Carnitine in hemodialysis patients.
کلیدواژه‌های انگلیسی مقاله
نویسندگان مقاله محمد رضا صبری | mohammad reza sabri
child growth and development research center, department of pediatric cardiology, school of medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

فرناز فهیمی | farnaz fahimi
department of radiology, school of medicine, kerman university of medical sciences, kerman, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

سهیلا hajialiasgar | soheila hajialiasgar
department of radiology, school of medicine, kerman university of medical sciences, kerman, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

عباس اطمینان | abbas etminan
department of nephrology, school of medicine, kerman university of medical science, kerman, iran


سریر ناظمی | sarir nazemi
department of radiology, school of medicine, kerman university of medical sciences, kerman, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی کرمان (Kerman university of medical sciences)

فرزانه صالحی | farzaneh salehi
dialysis ward, shafa hospital, kerman university of medical science, kerman, iran.
نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/8359
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده
نوع مقاله منتشر شده Original Articles
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات