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Journal of Research in Medical Sciences، جلد ۱۷، شماره ۸، صفحات ۰-۰
عنوان فارسی
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عنوان انگلیسی A comparison between cetirizine and ondansetron in preventing postoperative nausea and vomiting in adults
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 Background: Postoperative nausea and vomiting are some of the important and common side effects of anesthesia after surgery occurring in almost 20-30% of patients and is the second factor of a patient’s complaint and inconvenience after pain. This study compares the effect of oral cetirizine and ondansetron in the prevention of postoperative nausea and vomiting in adults. Materials and Methods: In a blind and prospective study in fall 2010, 300 patients aged 18-65 years who were among ASA І-П in Chamran Orthopedic Hospital were randomly divided into three equal groups receiving cetirizine, ondansetron, and placebo, respectively. General anesthesia was identical. After operation (after 1-2 h in the recovery room, after 2-12 and 12-24 h in the ward), the presence or absence and any nausea or vomiting was recorded. Results: The postoperative nausea and vomiting ( PONV) rate after 1-2 h in the recovery room, after 2-12 and 12-24 h in the ward in placebo, and both groups of cetirizine and ondansetron were 50%, 21%, and 11%, respectively while the difference was significant ( P value < 0.05). Regarding the number of vomiting, the least was related to ondansetron (especially in the first 2-12 h) but the difference was not significant ( P > 0.05). Conclusion: The PONV rate in cetirizine and ondansetron groups was less than the placebo group.
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نویسندگان مقاله سید m لهسایی | seyed m lahsaei
department of anesthesiology, anesthesiology research center, shiraz university of medical sciences, shiraz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)

دکتر افشین امینی | afshin amini
department of anesthesiology, anesthesiology research center, shiraz university of medical sciences, shiraz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)

سید m n طباطبایی | seyed m n tabatabei
department of anesthesiology, zahedan university of medical sciences, zahedan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی زاهدان (Zahedan university of medical sciences)

گلنوش مهربانی | golnoush mehrabani
stem cell and transgenic technology research center, shiraz university of medical sciences, shiraz, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شیراز (Shiraz university of medical sciences)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/8573
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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