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Journal of Research in Medical Sciences، جلد ۱۷، شماره ۹، صفحات ۰-۰

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عنوان انگلیسی Pharmacovigilance and drug safety 2011 in Calabria (Italy): Adverse events analysis
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 BACKGROUND: Pharmacovigilance assesses the safety profile of drugs. its main aim is the increase of spontaneous reporting of adverse drug reactions (ADRs).The Italian drug agency (AIFA; Agenzia Italianadel Farmaco) is financing several projects to the aim of increasing reporting, and in Calabria a pharmacovigilance information centre has been created. MATERIALS AND METHODS: We analysed the AIFA database relatively to Calabria in the year 2011 and we have analyzed ADRs using descriptive statistics. We have also collected a questionnaire-based interview in order to describe the background knowledge in the field. RESULTS: Regarding the number of AIFA reported ADRs from Calabria,a 38% increase (138 vs. 100) in comparison to 2010 was evidenced. hospital doctors represent the main source of signaling (%). Ketoprofene and the combination amoxicillin/clavulanic acid represent the most frequently reported drugs causing ADRs (%).our questionnaires indicated that despite the health professionals have met at least once an ADR only a small percentage of them was reported to the authorities (%).there is a very good knowledge of the ADR concept and reporting system (90% of interviewed distinguish an ADR and knows how to report it), and there is a strong interest in participating to training courses in the field (95% are interested). CONCLUSIONS: Despite Calabria has had a positive increase in the number of reported ADRs, the total number is very low and the pharmacovigilance culture is far from being achieved in this region.
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نویسندگان مقاله francesca scicchitano | francesca scicchitano
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy


chiara giofr㨠| chiara giofrã¨
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy


caterina palleria | caterina palleria
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy


carmela mazzitello | carmela mazzitello
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy


miriam ciriaco | miriam ciriaco
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy


luca gallelli | luca gallelli
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy


لورا paletta | laura paletta
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy


giuseppina marrazzo | giuseppina marrazzo
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy


سالواتوره de fazio | salvatore de fazio
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy


michele menniti | michele menniti
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy


rubens curia | rubens curia
settore 3 area lea,dipartimento tutela della salute e politiche sanitarie, regione calabria, italy


concetta arena | concetta arena
settore 3 area lea,dipartimento tutela della salute e politiche sanitarie, regione calabria, italy


serafina chimirri | serafina chimirri
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy


marinella patan㨠| marinella patanã¨
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy


stefania esposito | stefania esposito
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy


felisa cilurzo | felisa cilurzo
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy


orietta staltari | orietta staltari
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy


emilio russo | emilio russo
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy


giovambattista de sarro | giovambattista de sarro
department of science of health, school of medicine, university of catanzaro, italy and pharmacovigilance’s centre regione calabria, university hospital mater domini, catanzaro, italy



نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/8625
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