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Journal of Research in Medical Sciences، جلد ۱۸، شماره ۹، صفحات ۷۳۳-۰
عنوان فارسی
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عنوان انگلیسی The effect of lidocaine on reducing the tracheal mucosal damage following tracheal intubation
چکیده انگلیسی مقاله Normal 0 false false false EN-US X-NONE AR-SA MicrosoftInternetExplorer4 Background: The aim of this study was to investigate the efficacy of lidocaine solution in the cuff of the endotracheal tube in reducing mucosal damage following tracheal intubation. Materials and Methods: This was a randomized controlled trial study undertaken in the intensive care unit patients. Participants, who met all eligibility criteria, were randomly assigned to one of two groups of patients, according to whether lidocaine or air was used to fill the tracheal tube cuff. The tracheal mucosa at the site of cuff inflation was inspected by fiberoptic bronchoscopy and scored at the 24 h and 48 h after intubation. Results: In all, 51 patients (26 patients in the lidocaine group and 25 patients in the control group) completed the study. After 24 h, erythema and/or edema of tracheal mucosa were seen in 2 patients (7.7%) of lidocaine group and 6 patients (24%) of air group ( P = 0.109). Binary logistic regression analysis showed that lidocaine has a significant protective effect against mucosal damage (odds ratio = 0.72, confidence interval = 0.60-0.87). Conclusion: The inflation of the tracheal tube cuff with lidocaine was superior to air in decreasing the incidence of mucosal damage in the 24 h and 48 h post intubation.
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نویسندگان مقاله سعید عباسی | saeed abbasi
department of anesthesiology and intensive care, anesthesiology and critical care research center, alzahra university hospital, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

حسین mahjoubipoor | hossein mahjoubipoor
department of anesthesiology and intensive care, anesthesiology and critical care research center, alzahra university hospital, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

پرویز کاشفی | parviz kashefi
department of anesthesiology and intensive care, anesthesiology and critical care research center, alzahra university hospital, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

غلامرضا معصومی | gholamreza massumi
department of anesthesiology and intensive care, anesthesiology and critical care research center, alzahra university hospital, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

امید آقاداودی | omid aghadavoudi


زیبا فرج زادگان | ziba farajzadegan
department of community medicine, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

پروین ساجدی | parvin sajedi
department of anesthesiology and intensive care, anesthesiology and critical care research center, alzahra university hospital, isfahan university of medical sciences, isfahan, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی اصفهان (Isfahan university of medical sciences)

نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/9464
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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