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Journal of Research in Medical Sciences، جلد ۲۰۱۴، شماره ۰۱، صفحات ۰-۰

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عنوان انگلیسی An Outcome Measure of Functionality and Quality of Life in Patients with Osteoporotic Vertebral Fracture: A Validation Study of the QUALEFFO-41
چکیده انگلیسی مقاله Background: Osteoporosis is a very common disease of bone, and vertebral fracture. The Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO-41) is a tool of health related quality of life in these patients. This study aimed to cross-culturally translate and validate the QUALEFFO-41 in Iran. Materials and Methods: This was a prospective clinical validation study. Forward-backward procedure was used to translate the questionnaire from English into Persian. The translation and cross-cultural adaptation was made in accordance with published guidelines. Patients were divided into two study groups, according to World Health Organization criteria: with at least one vertebral fracture, which had been surgery and with OP and no fractures as a control group. All of the participants were assessed by both QUALEFFO-41 and SF-36. Surgery group was asked to respond to the QUALEFFO-41 at two points in time: pre- and postoperative assessments (6 months follow-up). To test reliability the internal consistency was evaluated using Cronbach's alpha coefficient. Validity was evaluated by performing convergent validity between the QUALEFFO-41 and the SF-36 and Item-scale correlations, and discriminatory ability. Internal responsiveness of the QUALEFFO-41 to the clinical intervention (surgery) also was evaluated comparing patients’ pre- and postoperative scores. Results: In all 149 patients were completed the questionnaire, 48 patients with surgery, and 101 patients as a control group. The QUALEFFO-41 at pre- and postoperative assessments showed adequate internal consistency in all domains (Cronbach's alpha of 0.71 to 0.81). Additionally, the correlation of each item with its hypothesized domain of the QUALEFFO-41 indicated acceptable results suggesting that the items had a substantial relationship with its own domain. Further analysis also indicated that the questionnaire was responsive to change (P < 0.0001). Significant correlations existed between scores of similar subscales of QUALEFFO-41 and the SF-36 (P < 0.001). Conclusions: The findings show that, the Iranian version of QUALEFFO-41 is a reliable and valid measure of functionality and quality of life evaluation among patients with osteoporotic vertebral fracture. Keywords: QUALEFFO-41, Measure, Osteoporotic vertebral fracture Normal 0 false false false EN-US X-NONE AR-SA /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0cm 5.4pt 0cm 5.4pt; mso-para-margin:0cm; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:Arial; mso-bidi-theme-font:minor-bidi;}
کلیدواژه‌های انگلیسی مقاله QUALEFFO-41, Measure, Osteoporotic vertebral fracture

نویسندگان مقاله دکترپریسا عظیمی | parisa azimi
department of neurosurgery, shahid beheshti university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

shirzab اظهری | shirzab azhari
department of neurosurgery, shahid beheshti university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)

علی منتظری | ali montazeri
department of neurosurgery, shahid beheshti university of medical sciences

سازمان اصلی تایید شده: دانشگاه علوم پزشکی شهید بهشتی (Shahid beheshti university of medical sciences)


نشانی اینترنتی http://jrms.mui.ac.ir/index.php/jrms/article/view/9746
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زبان مقاله منتشر شده en
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نوع مقاله منتشر شده Original Articles
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